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1.
Opt Express ; 27(20): 27962-27978, 2019 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-31684556

RESUMO

Low-frequency conversion efficiency severely limits the 3ω ultraviolet energy density at the target of inertial confinement fusion facilities. Here, we present a bio-inspired surface aberration mitigation (SAM) technique that could significantly reduce the crystal surface aberration and realize high frequency conversion efficiency over a clear aperture of 400 mm × 400 mm. Numerical models are utilized to optimize and verify the mechanical properties and physical performance of the SAM technique. In addition, the influences of various operation conditions on surface aberration, angle-detuning magnitude, and frequency conversion efficiency are illustrated. Finally, the process stability and online feasibility of this new approach are validated by the established offline characterization system and in situ imaging system.

2.
Opt Express ; 22(18): 22157-62, 2014 Sep 08.
Artigo em Inglês | MEDLINE | ID: mdl-25321590

RESUMO

In this paper, a multiple folded resonator is presented which consists of a multiple optical folding setup, a flat total reflector, a flat output coupler, a Q-switch crystal and a polarizer. By this technique, the output energy of 32.6mJ and pulse width of 13.4ns with a repetition rate of 5Hz was obtained, which is three times higher than that reported in the past publications by the use of the currently existing technique of the Q-switched slab gain lasers with the unstable resonator. The output beam with a quality of M² = 1.55 in the slow axis and M² = 1.40 in the fast axis was also obtained.

3.
Zhong Xi Yi Jie He Xue Bao ; 2(6): 450-2, 2004 Nov.
Artigo em Chinês | MEDLINE | ID: mdl-15539027

RESUMO

OBJECTIVE: To study the pharmacological activities and toxicity of the crude alkaloids of Toddalia asiatica and to provide pharmacological data for the further development of this herbal medicine. METHODS: We observed the anti-inflammatory effects of the crude alkaloids of Toddalia asiatica, using xylol and agra to induce the turgidness and sodium carboxymethyl cellulose (CMC-Na) to induce leucocyte strolling in the rats. The analgesic effects were observed by body-distortion methods. The effects of alkaloids of Toddalia asiatica on hepatic function were observed by testing the contents of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in serum and calculating the liver index. The LD 50 and 95% creditability were calculated with developed Karber Method. RESULTS: The administration of alkaloids of Toddalia asiatica had the function of inhibiting the auricle swelling caused by xylol and joint swelling caused by agar and leucocyte migration caused by CMC-Na, decreasing the body-distortion of the rats. After two weeks administration, the contents of ALT and AST showed that there was no obvious difference between administered group and control group. The LD50 of the crude alkaloids of Toddalia asiatica was 1.622 g/kg and the 95% creditability was 1.29-2.03 g/kg. CONCLUSION: Toddalia asiatica has anti-inflammatory and analgesic effects, and there is no injury to the liver after long-term administration in rats.


Assuntos
Alcaloides/farmacologia , Anti-Inflamatórios não Esteroides/farmacologia , Anti-Inflamatórios/farmacologia , Rutaceae/química , Alanina Transaminase/metabolismo , Alcaloides/uso terapêutico , Animais , Anti-Inflamatórios/uso terapêutico , Anti-Inflamatórios não Esteroides/uso terapêutico , Relação Dose-Resposta a Droga , Feminino , Glutamil Aminopeptidase/metabolismo , Leucócitos/efeitos dos fármacos , Fígado/efeitos dos fármacos , Fígado/enzimologia , Masculino , Camundongos , Parassimpatolíticos/farmacologia , Parassimpatolíticos/uso terapêutico , Fitoterapia , Extratos Vegetais/efeitos adversos , Extratos Vegetais/farmacologia , Extratos Vegetais/uso terapêutico , Raízes de Plantas/química , Ratos
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